finds proxy SNPs from an internal reference (DECODE format)

finds proxy SNPs from an internal reference (DECODE format)

Usage

proxy_search_DECODE(
  data_exposure,
  data_outcome,
  data_outcome_path,
  data_reference,
  data_reference_path,
  tag_r2 = 0.8,
  tag_kb = 5000,
  tag_nsnp = 5000,
  outcome_sep
)

Arguments

data_exposure

Data frame containing exposure SNP data.

data_outcome

Data frame containing outcome SNP data.

data_outcome_path

Path to the outcome data file.

data_reference

Data frame containing reference SNP data.

data_reference_path

Path to the reference data file.

tag_r2

Threshold for LD (default: 0.8).

tag_kb

Threshold for distance in kb (default: 5000).

tag_nsnp

Threshold for number of SNPs (default: 5000).

outcome_sep

Delimiter used in the outcome data file.

Value

Data frame with proxy SNPs added.